O que (quem) é P53 - definição
P53
![p53 immunostain]].](https://commons.wikimedia.org/wiki/Special:FilePath/Anaplastic astrocytoma - p53 - very high mag.jpg?width=200 "p53 immunostain]].")
![Overview of signal transduction pathways involved in [[apoptosis]]](https://commons.wikimedia.org/wiki/Special:FilePath/Signal transduction pathways.svg?width=200 "Overview of signal transduction pathways involved in [[apoptosis]]")
MAMMALIAN PROTEIN FOUND IN HOMO SAPIENS
P53 gene; Protein P53; P53 protein; Tumor suppressor p53; Phosphoprotein p53; Antigen NY-CO-13; Cellular tumor antigen p53; TP53 gene; TP53 (version 2); Tumor suppressor protein p53; The guardian of the genome; Genes, p53; P53 expression; P53 (protein); TP53 (gene); TRP53; Tp53 Gene; P53 tumor suppressor; Tumor protein; P53 signaling pathway; TP53; Guardian of the Genome
Tumor protein P53, also known as p53, cellular tumor antigen p53 (UniProt name), the Guardian of the Genome, phosphoprotein p53, tumor suppressor p53, antigen NY-CO-13, or transformation-related protein 53 (TRP53), is any isoform of a protein encoded by homologous genes in various organisms, such as (humans) and Trp53 (mice). The p53 proteins (originally thought to be, and often spoken of as, a single protein) are crucial in vertebrates, where they prevent cancer formation.
P53 (band)
EXPERIMENTAL MUSIC GROUP
"Thomas Dimuzio"; Thomas Dimuzio
p53 was an experimental music group commissioned by English percussionist Chris Cutler to play at the 25th Frankfurt Jazz Festival in Germany in September 1994. Their performance was recorded and released by Recommended Records in 1996 on a live album entitled p53.
HMS Ultor
SUBMARINE OF THE ROYAL NAVY
HMS P53 (1942); HMS Ultor (P53)
HMS Ultor (P53) was a Royal Navy U-class submarine built by Vickers-Armstrong at Barrow-in-Furness, launched in 1942, and part of the third group of the class. So far she has been the only ship of the Royal Navy to bear the name Ultor.
Exemplos de pronúncia para P53
1. So P53?
Brian Druker _ Talks at Google
2. there's probably P53 in there.
Brian Druker _ Talks at Google
3. It's three proteins: ras, myc, p53.
ted-talks_1256_JayBradner_2011X-320k
4. There's no ras, no myc, no p53 drug.
ted-talks_1256_JayBradner_2011X-320k
5. can see this P53 mutation's in 57% of the reads,
David Solit _ Talks at Google
Exemplos do corpo de texto para P53
1. When p53 itself becomes disabled by mutations, though, cells can more easily turn cancerous.
2. One is to use gene therapy to insert normal copies of the p53 gene into cancer cells.
3. The company‘s studies, most of them published only in Chinese medical literature, showed significant benefits, if not cures, from the p53 treatment.
4. "We think that the high risk of breast cancer may be related to an unusually high level of certain hormones during pregnancy – which is also due to inheriting an abnormal copy of the p53 gene.
5. The mutation of a gene known as p53 – which all of us have and which normally suppresses cancer – could mean that mothers and their children are more susceptible to the disease.